Oil of DermaeHerbal Products


Dried Papaya Leaf Capsules


1-2 Capsules, 6-8 hourly or as recommended by your physician


Dr. SanathHettige (MBBS, DFM, MD, FCGP) Chief Scientist of Oil of Dermae Laboratories holds the patent rights in Sri Lanka for three processes for commercially preparing papaya leaf extract for dengue fever patients and other relevant diseases proven for its benefits. The capsules are produced commercially in our own ayurvedic research laboratory.

Dr. SanathHettige won the Presidential Award for best medical invention for 2013 at the Presidential award ceremony held on the 5th of February 2016 for his invention of papaya leaf syrup, tablets and capsules for the treatment of dengue fever and other medical conditions and the Silver Award for Papaya Leave Capsule at the International fair at Bangalore , India.

For further information on product & Research please refer:

Dengue fever


1) Dengue fever

Dr. Sanath Hettige in 2008 discovered that papaya leaf juice was helpful in the treatment of Dengue fever. This discovery was published in Sri Lanka Family Physician Journal 2008, 29, 17-19 (1). Following this study many research have been done world over. These studies have shown the following medical benefits.

  • Reduction in conversion of Dengue fever to Dengue hemorrhagic fever (Anti-leaking properties) (2)
  • Stimulation of the hematopoietic system which stimulates Platelet production, White Blood Cell production and Red Blood Cell production ( 1, 2, 3, 4, 5, 6, 7 )
  • Speedy recovery with reduced hospitalization 1
  • In-vitro erythrocyte membrane stabilization properties (6)
  • Stimulates the immune system, which enhances the activity against the viral infections (7)
  • Direct anti-viral activity on dengue virus (4)
  • Animal studies have shown that it prevents chemically induced capillary leakage in Mice (8)
  • Toxicology studies ruled out any significant toxic effects even at higher doses (9)

Researches have not shown only a solitary rise in platelet count without the patient’s condition being improved. The rise in the platelet count observed in patient taking PAPAYACAP is due to the overall improvement of the disease process (10).

During the recent dengue epidemic in Sri Lanka from 1st June to 31st August 2017, which was the largest epidemic, reported due to type II dengue strain, 385 patients consumed PAPAYACAP. An observational study of these patients is published in Sri Lanka family physician, 2017, 33, 21-26. In this study only two patients needed ICU treatment and there were no reported deaths.

This study has proven the efficacy and the safety profile of the PAPAYACAP.

Dosage and Method of use of PAPAYACAP in dengue fever patients

You can confirm that fever is due to dengue fever by performing NS1 Ag test in the first 3 days of fever. You can take PAPAYACAP 2 capsules 6-8 hourly depending on the severity of their disease and body weight as advised by a physician.

PAPAYACAP should be taken while on usual dengue management as recommended by your physician. You can continue PAPAYACAP for about 5-10 days until your platelet count comes to normal levels.

PAPAYACAP could be given at any stage of illness but for best result, it should be given within the first 3 days of the illness.

For people who cannot swallow capsules, PAPAYACAP could be taken as an herbal tea by emptying 2 capsules of PAPAYACAP to 250ml of boiling water, mix and let it brew for 5 minutes.

This could be taken sip by sip for over a period of 1 hour or more.

Dengue is a serious illness with potentially lethal complications. It is strongly advised to seek medical help immediately when diagnosed with Dengue. PAPAYACAP is only a supportive treatment that could be used with recommended Dengue management.

More information about Dengue management please click the link below

Dengue Sinhala leaflet booklet | Dengue English leaflet booklet

2) Cancer

PAPAYACAP could be used in cancer patients

  • To increase the production of White Blood Cells, Platelets and Red Blood Cells which has been lowered as a result of chemotherapy.
  • As a direct anti-cancer agent (anti-tumor activity) Research and case reports have shown that papaya leaf extracts exhibits anti-cancer properties.

Dosage and Method of use of PAPAYACAP in Anti- Cancer activities

1-2 capsules 6-8 hourly or as recommended by your physician. Treatment could be continued as long as it is necessary. Research have not shown any renal hepatic toxicity or interaction with other drugs.

3) Diabetes

Papaya leaves helps in the control of blood sugar by regulating the production of Insulin. PAPAYACAP helps in maintaining Blood glucose levels in Diabetics and reduces the drugs and Insulin dosage. Its strong anti-oxidant nature also helps to bring down the consequent complications of diabetes like kidney damage and fatty liver.

Dosage and Method of use of PAPAYACAP in Diabetes

1-2 capsules should be taken daily, ½ hour before meal with a full glass of water. It could be taken alone or combine with other anti-diabetic medication and Insulin.

PAPAYACAP may potentiate the activation of anti-diabetic drugs and Insulin. Therefore it may be necessary to reduce the dosage of anti-diabetic drugs and Insulin when using in combination with PAPAYACAP.

4) Supports digestion and prevents Constipation

The two enzymes found in Papaya, papain and chymon-papain, both have been shown to aid digestion, prevent constipation and clean the colon. Papain is also helpful in healing and preventing stomach ulcers.

Dosage and Method of use ofPAPAYACAP for constipation

1-2 capsules should be taken daily, ½ hour before meal with a glass full of water.

5) Menstrual Pain

Papayaeases the menstrual flow,reduces the pain andalso brings down Pre Menstrual Syndrome symptoms. It’s potent healing properties balances hormones, and regulates menstruation cycles.

Dosage and Method of use ofPAPAYACAP for constipation

1 capsule 2 times a day during the menstruation period starting from the first day.

6) Healthy Skin

Papaya has a rich content of vitamin C and A which boost skin health and gives a healthier and radiant skin. It suppresses the activity of free radicals, checks the growth of excess micro-organisms and cleanses your skin of the toxins, providing protection against skin problems like pimples, freckles and acne.

Dosage and Method of use of PAPAYACAP for constipation

1 capsule 2 times a day

7) Hair growth

The extract of papaya leaf is said to promote hair growth, prevent balding and thinning of hair. It can also serve as a natural conditioner and bring back the lost sheen to your hair.

Dosage and Method of use of PAPAYACAP for constipation

1 capsule 2 times a day


No major side effects have been shown in rat studies using large doses of papaya leaf extracts. Large scale randomized controlled clinical trials in Dengue fever have not shown any major side effects.

Bitter induced vomiting and ulceration of mouth have been reported in few cases using pure papaya leaf juice. But not seen with PAPAYACAP capsules.

However allergic reaction can occur in-patient allergic to Papaya.

Anti-diabetic and Insulin should be reduced in diabetic patients when using PAPAYACAP. Hypoglycemic effects have not been shown in normal people.